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It has been recognized since the 1940s that vitamin E (-tocopherol) is a powerful lipophilic antioxidant that is absolutely vital for the maintenance of mammalian spermatogenesis.24 It is present in particularly high amounts in Sertoli cells and pachytene spermatocytes and to a lesser extent round spermatids.25 Vitamin C (ascorbic acid) also contributes to the support of spermatogenesis at least in part through its capacity to reduce -tocopherol and maintain this antioxidant in an active state

In improving the behavioral performance of mice, Lactobacillus rhamnosus JB-1 was included and found to affect the expression of GABA receptors in the brain in a region-dependent manner

The role of MMP genes in recurrent depressive disorders and cognitive functions